Regeneron's strategy focuses on a broad pipeline across six therapeutic areas, with significant near-term data readouts ...
TSP-1 reduced C3 and C5 cleavage and formation of the membrane attack complex, attenuating complement-mediated injury in AAV models. Complement activation is a relevant driver in the pathomechanisms ...
Pegcetacoplan significantly reduces proteinuria in patients with recurrent C3 glomerulopathy, or primary immune-complex ...
Imlifidase is more effective than standard of care plasmapheresis at removing donor-specific antibodies after kidney transplantation. Imlifidase more effectively reduces donor specific anti-HLA ...