Mutations that affect the adaptor molecule SLAM-associated protein (SAP) lead to the genetic disorder X-linked lymphoproliferative syndrome (XLP), which is characterized by severe, often fulminant ...
SAP (signalling lymphocytic activation molecule (SLAM)-associated protein) is a cytoplasmic protein that consists of a single SH2 domain with a 28-amino-acid tail. The gene encoding SAP is defective ...
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