A receptor that cannabis latches onto in the brain could be a promising target for future mental health treatments. Experiencing chronic stress is known to leave people vulnerable to depression or ...

When faced with chronic stress, why do some people develop anxiety and depressive symptoms while others show resilience? The results of studies in mice, headed by researchers at Université Laval, ...

In From Bud to Brain, I traced how marijuana research gradually morphed from focusing on the cannabis plant (botany) to exploring the brain’s natural endocannabinoid system (neuroscience) and, ...

Neuroscientist Rogier Min from the Amsterdam UMC has collaborated with Christiaan Levelt’s lab from the Netherlands Institute for Neuroscience and discovered how brain cells may react to cannabis, ...

When faced with chronic stress, why do some people develop anxiety and depressive symptoms while others show resilience? A protein that acts as a cannabinoid receptor and is present in the structure ...

A new study found that cannabis affects brain development by interacting with CB1 receptors on astrocytes. The findings indicate that disrupting CB1 receptor activity during development, such as via ...

BORDEAUX, France — Could AEF0117, a drug that has a novel mechanism of action in the brain, be the drug to fight cannabis addiction? Results from a phase 2a clinical trial that examined the efficacy ...

The efficacy of cannabinoid CB1 receptor antagonists in diet-induced obesity and its related metabolic complications is well established, but they are tied to central nervous system (CNS)-related ...

Cannabinoid CB1 receptors have been a potential target for nonopioid-based pain treatment, but actually targeting the pathway has been hindered by issues with tolerance and unwanted CNS side effects.