A new article analyzes in depth the physical problems associated with DNA packaging that have often been neglected in structural models of chromosomes. The study demonstrates that the multilaminar ...

A detailed map of human chromosomes within the nucleus is presented in Nature this week. This resource provides a foundation for an improved understanding of how the physical layout of human DNA is ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, No. 5 (February 4, 2020), pp. 2241-2242 (2 pages) D. Krepel, A. Davtyan, N ...

This study is led by Prof. Shunxin Wang (State Key Laboratory of Reproductive Medicine and Offspring Health, Center for Reproductive Medicine, Institute of Women, Children and Reproductive Health, ...

A research team has uncovered the profound effects of an atypical mode of chromosome arrangement on genome organization and evolution. A research team led by André Marques at the Max Planck Institute ...

Chromosome with loops (on the left) and the peak-dip derivative curve of the contact probability (on the right). On large and small scales, chromosome folding differs significantly due to the ...

A research team led by André Marques at the Max Planck Institute for Plant Breeding Research in Cologne, Germany, has uncovered the profound effects of an atypical mode of chromosome arrangement on ...

Despite their utility, everyday essentials—cosmetics, food packaging, plastics—can contain endocrine-disrupting chemicals (EDCs). These stealthy invaders can slip into the body through skin absorption ...

Edwards syndrome, also known as trisomy 18, describes a rare genetic condition where a person has three copies of chromosome 18. Having an extra copy of this chromosome causes a variety of symptoms ...