Here, we report a practical method for the fast and highly selective direct cross-coupling of organolithium reagents under mild conditions, and with broad scope, using Pd catalysis. Catalytic C–C bond ...

Non-precious-metal catalysts are increasingly employed for commercial API synthesis. Cross-coupling reactions enable the synthesis of complex building blocks and intermediates with structural motifs ...

Figure 1: Suzuki–Miyaura cross-coupling reactions with enantioenriched secondary alkyl boronate derivatives. An attractive, logical evolution of this powerful approach would consist in achieving ...

Alternatives to expensive palladium catalysts are gaining acceptance for commercial API synthesis. Cross-coupling reactions enable the synthesis of complex building blocks and intermediates with ...

Cross-coupling has been one of the most popular types of reactions in organic chemistry for decades. The pharma and agrochemical industries use these methods on a large scale to forge bonds between ...