This is a preview. Log in through your library . Abstract The myo-inositol oxidation pathway was investigated in regard to its role as a source of carbon for products of hexose monophosphate ...

We next determined the effect of inositol polyphosphates on Akt kinase activity in SCLC-H69 cells by using an in vitro kinase assay. Ins(1,3,4,5,6)P 5 inhibited Akt kinase activity (43±3% inhibition ...

In the mid 1980s we discovered a phosphatidylinositol kinase that co-purified with several oncoproteins and that correlated with cell transformation. When my graduate student Malcolm Whitman presented ...

Inositol phosphates are crucial secondary messengers that modulate a wide range of cellular processes, from energy metabolism to gene expression. These molecules, particularly inositol pyrophosphates, ...

The protein 'MIPS' changes its internal structure when it becomes active. Its disordered active centre becomes a defined structure with special functions. The protein plays a key role in the ...

We previously identified the lpa1 (low phytic acid) 280-10 line that carries a mutation conferring a 90% reduction in phytic acid (InsP₆) content. In contrast to other lpa mutants, lpa1(280-10) does ...

Inositol is a sugar required for cells to survive. Most cells either get it from the bloodstream or make it themselves. Since there is plenty of inositol available, some cancer cells decide to stop ...

Inositol is a sugar required for cells to survive. Most cells either get it from the bloodstream or make it themselves. Since there is plenty of inositol available, some cancer cells decide to stop ...

Inositol belongs to the vitamin B family and is often referred to as vitamin B8, although it is not officially classified as a vitamin. It is rather a type of sugar with several important functions.

Although it’s often referred to as vitamin B8, inositol is not a vitamin but rather a type of sugar with several important functions. It influences the action of insulin and may aid mental health and ...