Shroom3 mutation linked to kidney scarring offers new drug target

Nearly 1 in 7 adults in the United States lives with chronic kidney disease, a condition that often advances quietly until ...
Nasdaq

BIO-TECHNE LAUNCHES ESR1 MUTATION MONITORING ASSAY

Company will showcase new assay at the upcoming San Antonio Breast Cancer Symposium While mutations in the ESR1 gene are exceedingly rare in cancer patients prior to treatment, the use of endocrine ...
Morning Overview on MSN

Evolution just broke its own logic, a new biology rule may follow

Biologists are closing in on a puzzle that seems to turn classic evolutionary logic inside out, yet may be so common that it ...
eLife

Separating selection from mutation in antibody language models

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...
BioTechniques

Novel technique detects early DNA mutations

A new long-read sequencing technique has helped researchers investigate how DNA mutations arise in a variety of contexts. A collaboration of researchers led by NYU Langone Health and NYU Grossman ...
BioWorld

Mutation-specific targeting increases transporter protein in cystic fibrosis

A study published in Nature Communications revealed a new antisense oligonucleotide (ASO) therapy applicable to the W1282X mutation of the cystic fibrosis transmembrane conductance regulator gene ...
BioWorld

For mutations, "synonymous" is not a synonym for silent, study finds

A central assumption about so-called synonymous mutations, which are changes in the coding sequence of proteins that do not lead to changes in its amino acid sequence, is being questioned by a study ...