Despite the replacement of the monoamine hypothesis of depression with a more comprehensive understanding of multiple influencing factors in the pathology of depression, it is clear that elevating ...

'Red flag' symptoms of monoamine neurotransmitter disorders include diurnal variation of symptoms, a mixed movement disorder, autonomic disturbance, involvement of the eyes (ptosis, oculogyric crisis) ...

Fifty-plus years ago, Julius Axelrod and his colleagues discovered the phenomenona of neurotransmitter inactivation by reuptake into the nerve terminal, a finding that led to the development of ...

5-hydroxytryptophan (5-HTP) is a naturally occurring amino acid and the essential precursors of serotonin (5-hydroxytryptamine) an important neurotransmitter for mood regulation, memory, learning, and ...

A novel structure of a so-called 'neurotransmitter: sodium symporter’ has been mapped at the University of Copenhagen. The discovery adds to the researchers’ knowledge of neurotransmitters in the ...

Many details have recently been worked out describing events in any brain exposed to the most common addictive drugs: heroin, morphine, barbiturates, tranquilizers, and alcohol (all depressants that ...

Antidepressants have been touted for decades as a go-to treatment for depression, but some of them are under scrutiny with a study released this week. It turns out that selective serotonin reuptake ...

The brain chemicals behind your mood, sleep, and body functions Medically reviewed by Shaheen Lakhan, MD, PhD, FAAN Ever wonder what's going on in your brain when a certain mood strikes? You can thank ...

In 2015, Harel Weinstein’s team used the Titan supercomputer at the US Department of Energy’s (DOE’s) Oak Ridge National Laboratory (ORNL) to produce the first end-to-end simulation of a sodium ion, ...

A novel structure of a so-called 'neurotransmitter: sodium symporter' has been mapped. The discovery adds to the researchers' knowledge of neurotransmitters in the brain and may lead to better drugs ...

After five years of experimentation, researchers from the University of Copenhagen have succeeded in crystallising and mapping a novel conformation of LeuT, a bacterial protein that belongs to the ...