The hormone estrogen—which female animals typically have more of than males—triggers a molecular cascade in the gut that ...

Scientists have re-created a pain pathway in the brain by growing four key clusters of human nerve cells in a dish. This laboratory model could be used to help explain certain pain syndromes, and ...

Men and women experience pain differently, and until now, scientists didn’t know why. New research says it may be in part due to differences in male and female nerve cells. Pain-sensing nerve cells ...

Stanford Medicine investigators have replicated, in a lab dish, one of humans' most prominent nervous pathways for sensing pain. This nerve circuit transmits sensations from the body's skin to the ...

Recent studies are pointing to the fact that kindness can decrease pain and lessen stress. As Dr. Kapoor notes, pain is largely an evolutionary mechanism to enhance survival and, hence, is largely ...

Stanford Medicine investigators have replicated, in a lab dish, one of the most prominent human nervous pathways for sensing pain. This nerve circuit transmits sensations from the body’s skin to the ...

In a fascinating discovery, scientists have pinpointed what happens in our brains when we're expecting pain relief but are given a placebo, unknowingly, instead. It not only confirms 'the placebo ...

Researchers at Tulane University, with a team of colleagues from eight other universities, have discovered a new nerve cell signaling mechanism that could transform our understanding of pain and lead ...

Please provide your email address to receive an email when new articles are posted on . An opioid-free protocol yielded noninferior pain scores vs. an opioid-containing protocol at 24 hours after ...

René Descartes gave a colorful description of the mechanism of pain in the 17th Century: "Particles" of fire set in motion a spot on the skin of the foot, and by means of a "delicate thread" they open ...

Researchers integrated four organoids that represent the four components of the human sensory pathway, along which pain signals are conveyed to the brain. Stimulation of the sensory organoid (top) by ...