There are cells in the body known as pluripotent stem cells that are yet to specialize in a particular biological function. These cells maintain the potential to become any of the possible cell types ...

Life begins with a tiny orchestra of stem cells, setting the stage for the body’s grand symphony of development. As the performance unfolds, a dynamic interplay of factors takes center stage, ...

New research shows that certain primate stem cells have pluripotency superior to some types derived from mice. The study maps how pluripotency differs among mice, monkeys, and humans, and illustrates ...

Not all stem cells possess an equal potential to produce specialized cell types. The sum potential of a cell to give different specialized cell types is called ‘potency’. ESCs possess pluripotency.

Pluripotency is highly dynamic in vivo and evolves at different stages of pre- and post-implantation development. However, the feature of self-renewal is a highly useful in vitro artificial phenotype ...

Scientists have found a control switch that regulates stem cell "pluripotency," the capacity of stem cells to develop into any type of cell in the human body. The discovery reveals that pluripotency ...

Multiplex Gene-Expression Assay for Human Induced Pluripotent Stem Cells Recent methods to reprogram human somatic cells in order to create induced pluripotent stem cells (iPSCs) are intended to ...

Despite pluripotent stem cells sharing key transcription factors, their maintenance involves distinct genetic inputs. Emerging evidence suggests that super-enhancers (SEs) can function as master ...

With a Kobe University-developed procedure, induced pluripotent stem cells can now be frozen directly in their dishes without ...

There are cells in the body known as pluripotent stem cells that are yet to specialize in a particular biological function. These cells maintain the potential to become any of the possible cell types ...

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein response (UPR mt) serves as an important retrograde regulatory pathway that ...