ETX-19477 is a potent, selective inhibitor of poly (ADP-ribose) glycohydrolase (PARG), an enzyme that plays a role in the DNA ...

Amenis Bioscience Inc. has identified anthranilic acid derivatives acting as peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (PIN1) and viral replication inhibitors reported to be useful for ...

Aligos Therapeutics Inc. has divulged bicyclic compounds acting as viral replication inhibitors reported to be useful for the treatment of hepatitis B (HBV) and hepatitis D virus infections.

Infection with cytomegalovirus (CMV) is extremely common, but the virus only becomes pathogenic when the immune system is weakened, by, for example, HIV or anti-rejection transplant immunosupressors.

These two images demonstrate synthetic lethality with a non-responsive cell line (right) compared to a responder to ATR +PKMYT1 inhibition (left). As demonstrated by the long strands, the ...