Regulation of cellular levels of ADP-ribose is important in preventing nonenzymatic ADP-ribosylation of proteins. The Escherichia coli ADP-ribose pyrophosphatase, a Nudix enzyme, catalyzes the ...
What made ribose the sugar of choice for life's code? Scientists at Scripps Research may have cracked a major part of this mystery. Their experiments show that ribose binds more readily and ...