The team analyzed the somite segmentation process that results in the formation of the vertebral column. This process is thought to be controlled by two components: a molecular oscillator (the ...

The Stowers Institute’s Pourquié Lab has demonstrated the importance of Beta-catenin, a key component of the Wnt-signaling pathway in the process of somite formation. The work has been published on ...

Vertebrates have a pretty diverse array of body plans, and one of the reasons for this is some evolutionary flexibility in the length of their primary body axis, the one that runs from head to tail.

Scientists have recapitulated in the laboratory how the cellular structures that give rise to our spinal column form sequentially. They have created a 3D in vitro model that mimics how the precursor ...

This video shows formation of somites in a normal embryo. For more information, please see Movie S3 in the Supporting Online Material. This video relates to a paper that appeared in the 9 Jan., 2014, ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, No. 22 (May 31, 2011), pp. 9160-9165 (6 pages) FGF signaling is one of the few cell—cell signaling pathways ...

The experimental analysis of chick limb bud development / J.W. Saunders Jr. -- In-vitro analysis of the distribution and nature of a morphogenetic factor in the developing chick wing / J.A. MacCabe, A ...

The spinal column is the central supporting structure of the skeleton in all vertebrates. Not only does it provide a place for muscles to attach, it also protects the spinal cord and nerve roots.