Medscape

Evaluating Hormonal Mechanisms of Vitamin D Receptor Agonist Therapy in Diabetic Kidney Disease: The VALIDATE-D Study

In light of these novel human results translated from animal experiments, we hypothesize that activation of the VDR represents a method to lower renal-vascular tissue-RAS activity in human diabetes, ...
Nature

Regulation of a novel angiotensin II precursor, proangiotensin-12, in the tissues by blockade of the renin–angiotensin system

In this study, Nagata et al. demonstrated that both treatments with an Ang II type 1 receptor blocker (ARB) and an ACE inhibitor (ACEi) suppressed blood pressure in SHR, and these treatments increased ...
Business Insider

Sysmex-Inostics Colorectal Cancer Blood-Based OncoBEAMTM RAS CE-IVD Test Shows Concordance with Standard of Care Tissue-Based RAS Testing

BALTIMORE, Aug. 5, 2020 /PRNewswire/ -- Sysmex-Inostics, Inc., a global leader and pioneer in blood-based circulating tumor DNA (ctDNA) analysis for oncology, today announces the publication of a ...
UUHC Health Feed

Renegades of Cell Biology: Why K-Ras Gene Mutations Prove So Deadly in Cancer

SALT LAKE CITY—Cells with a mutation in the gene called K-Ras—found in close to 30 percent of all cancers, but mostly those with worst prognosis, such as pancreatic cancer, colon cancer, and lung ...
Medscape

Evaluating Hormonal Mechanisms of Vitamin D Receptor Agonist Therapy in Diabetic Kidney Disease: The VALIDATE-D Study

The VALIDATE-D study will enroll 40 adults, aged 18–70 years, with Type 2 diabetes (T2DM), microalbuminuria, and without known CKD (estimated glomerular filtration rate > 60 mL/min). Subjects will be ...