Timing of troughs Troughs should be obtained at steady state: approximately prior to the fifth dose IIB Optimal trough concentrations Should be >10 mg/l at a minimum to avoid development of ...

Jennifer Le, PharmD Pediatric patients who attain higher trough levels of the drug may be at higher risk of kidney damage. SAN FRANCISCO—Nephrotoxicity from vancomycin therapy develops more quickly in ...

Guidelines recommend against use of midline catheters for vancomycin-based outpatient parenteral antimicrobial therapy (OPAT), but evidence supporting the guidance is limited. This retrospective study ...

Vancomycin is an effective glycopeptide antibiotic for gram-positive infections and is widely used to treat patients with methicillin-resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis ...

The vancomycin monitoring guidelines did not specifically address patients with several conditions such as severe renal dysfunction which might impact proper dosing. Vandecasteele and De Vriese ...