Species: Mouse Genes: LRRK2 Modification: LRRK2: Knock-In Disease Relevance: Parkinson's Disease Strain Name: C57BL/6-Lrrk2 tm4.1Arte Genetic Background: C57BL/6NTac Availability: Available through ...

This knock-in (KI) mouse model was generated by introducing a D427V point mutation into exon 10 of the mouse Gba1 (glucosidase, beta, acid 1) gene, which corresponds to the human D409V mutation (The ...

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