Secretin is a hormone that regulates water homeostasis throughout the body and influences the environment of the duodenum by regulating secretions in the stomach, pancreas, and liver.

Secretin is a digestive hormone secreted by the wall of the upper part of the small intestine (the duodenum) that regulates gastric acid secretion and pH levels, helping to maintain an optimal …

Secretin is secreted by S cells in the small intestine and affects the function of a number of organ systems. Secretin receptors (SR) are expressed in the basolateral domain of several cell types.

Jul 22, 2023 · Explore the physiology and role of secretin, a hormone involved in digestion. Learn about its production, secretion, target organs, and its impact on pancreatic secretion, bicarbonate …

Nov 4, 2025 · It is now known that secretin stimulates pancreatic fluid and bicarbonate secretion leading to neutralization of acidic chyme in the intestine. Secretin also inhibits gastric acid release and …

The principal target for secretin is the pancreas, which responds by secreting a bicarbonate-rich fluid, which flows into the first part of the intestine through the pancreatic duct.

Secretin is a natural endogenous peptide released from intestinal mucosa enterochromaffin cells. When binding to secretin receptors, secretin releases pancreatic fluid rich in bicarbonate and controls …

Secretin is predominantly produced in the S cells of the duodenum, the first segment of the small intestine. These cells release Secretin in response to the presence of acidic contents from the …

Nov 25, 2022 · Secretin is an intestinal hormone secreted by duodenal S-cells, mainly regulating the pancreatic secretion of bicarbonate and water (Henriksen and de Muckadell 2000).

Secretin was discovered in 1902 by William Bayliss and Ernest Starling, making it one of the first hormones identified. The release of secretin is triggered when acidic chyme enters the small …