Jul 29, 2024 · Tris-Hydroxymethyl Aminomethane (THAM or tromethamine) is an amino alcohol that acts as a buffer base that unlike NaBicarb doesn't increase Na or release CO2–it actually lowers PaCO2. …

Dec 17, 2024 · Tham package insert / prescribing information for healthcare professionals. Includes: indications, dosage, adverse reactions and pharmacology.

Mar 2, 2022 · Tham (tromethamine injection, solution) is a parenteral systemic alkalizer and fluid replenisher indicated for the prevention and correction of metabolic acidosis.

This review will discuss tris-hydroxymethyl aminomethane (THAM). THAM is a rarely used buffer approved by the Food and Drug Administration for treatment of metabolic acidosis associated with …

THAM (tromethamine injection) medication page for healthcare professionals to search for scientific information on Pfizer medications. Also find the prescribing information, announcements, resources, …

The intravenous administration of Tham Solution can cause fluid and/or solute overloading resulting in dilution of serum electrolyte concentrations, overhydration, congested states or pulmonary...

Tham Solution (tromethamine injection) should be administered slowly and in amounts sufficient only to correct the existing acidosis, and to avoid overdosage and alkalosis.

Dec 13, 2024 · Tham Solution (tromethamine injection) is a sterile, non-pyrogenic 0.3 M solution of tromethamine, adjusted to a pH of approximately 8.6 with glacial acetic acid.

Jul 28, 2025 · Tromethamine, often abbreviated as THAM, is a medication administered to help regulate the body’s pH balance. It functions as a “buffer,” directly interacting with and neutralizing excess …

Nov 1, 2023 · To clarify the evidence base supporting the clinical use of THAM, we conducted a systematic review to assess the efficacy and safety of THAM as a buffering agent in critically ill …