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How Sanger Sequencing Detects Thalassemia & Single-Gene Disorders
Dr. Purvi Agrawal explains Sanger sequencing, the classic method for targeted gene testing. Key points: Sanger sequencing focuses on one specific gene, e.g., thalassemia gene on chromosome 1. Confirms HPLC results and helps decide if fetal invasive testing is needed. Parent testing is important before checking the fetus, as HPLC can sometimes ...
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